The gut microbiome

This branch covers the gut microbiome, divided by the aspect a writer needs to understand: composition and development, disease associations, chronic pain, and therapies that alter it. General nutrition, inflammation and the clinical accounts of individual diseases belong to their own branches.

• The gut microbiome: what it is, how it develops and what it acts through — composition, functions, development from birth to adulthood, influences on diversity and interactions with other organs
• The gut microbiome in disease — disease associations, proposed pathways, uncertainty about causation and responsible public communication
• The gut microbiota and chronic pain — dysbiosis, peripheral and central pain sensitisation, treatment evidence and unresolved questions
• Therapies targeting the gut microbiome — approaches to modifying the microbiome, including faecal transplantation and synbiotics